Marker that diffuses freely not only in the water outside the cells but also crosses the cell membrane to reach the intracellular fluid. Human fluid volumes may be subdivided into several compartments.
Total Body Water Calculation Omni
Measurement of body fluid compartments pdf. Not interfere with body fluid distribution if the tracer is excreted in the urine then the loss can be determined and corrections made in the calculation. How to measure the volumes of body fluid compartments using marker substances. Endre sulyok md phd dsc in nephrology and fluidelectrolyte physiology. The differences in composition between the major body fluid compartments. In contrast skeletal muscle contains 75 water. After studying this lecture the student should understand.
18112012 14 copyright 2004 pearson education inc publishing as benjamin cummings. Measurement of body fluid volumes total body water is measured using dilution principle. Upon human body fluid changes that accompany a 21 day combined heat and exercise acclimation regime. Sinan canan created date. The intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranes. About two thirds is in the intracellular fluid compartment icf.
There are two main fluid compartments water occupies in the body. If the tracer is metabolised a series of measurements can be made and assuming exponential decline first order kinetics the volume of distribution can be determined by extrapolation back. Total body water tbw extracellular fluid ecfv plasma volume pv interstitial fluid ifv intracellular water icw red cell volume rcv and blood volume bv. Body fluids 1 and 2 linda costanzo phd. The distribution of water between the major body fluid compartments. Neonatology questions and controversies second edition 2012.
A marker is injected that will be evenly distributed in all the compartments of body fluids. Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrierthe intracellular fluid icf compartment is the system that includes all fluid enclosed in cells by their plasma membranesextracellular fluid ecf surrounds all cells in the body. Composition of fluid intra and extracellular. Ecf is further divided into interstitial extravascular and bloodplasma intravascular compartments. The intracellular fluid is the fluid within the cells of the body. How to measure the fluid volume intra and extra cellular total body water constitutes in men about 60 of body weight in women 50 is divided into icf and ecf.
The volume and composition of body fluid compartments are strictly controlled. Ecw is under neuroendocrine control and the final regulation is accomplished by the kidney through retaining or excreting solutes and fluids. So the more muscles one has the higher the total body water will be. Body fluids can be discussed in terms of their specific fluid compartment a location that is largely separate from another compartment by some form of a physical barrier.